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Brief description of study

The objective of the ISCHEMIA study is to determine the best management strategy for patients with stable ischemic heart disease and at least moderate ischemia on stress testing. It compares two standard treatments: 1) Starting treatment with cardiac procedures such as cardiac catheterization, and then stent placement or bypass surgery along with medicines and lifestyle changes. This is the invasive strategy. 2) Starting treatment with medicines and lifestyle changes alone, with a plan to use cardiac procedures only if medical therapy fails. This is the conservative strategy. The US National Heart, Lung, and Blood Institute of the National Institutes of Health is funding this research study, which will include thousands of participants with ischemia. Stable patients with ischemia and chronic kidney disease may be eligible to participate in the ISCHEMIA-CKD trial.

Clinical Study Identifier: NYU-0027

Principal Investigators: Nadeem Mehraj, Burhan Wani.

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Clinical Trials & Research Studies