Displaying 42 (all) recruiting clinical trials.
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A Phase 2 Double-blind Randomized Placebo-controlled Multicenter Study to Evaluate Efficacy Safety and Tolerability of JBT-101 in Systemic Lupus Erythematosus
This research study is being done to test the effect, safety, and tolerability of the experimental drug JBT-101 in subjects with Systemic Lupus Erythematosus (SLE ... -
A Phase 2/3 Randomized Double-Blinded Placebo-Controlled Parallel-Group Study to Investigate the Efficacy and Safety of Efgartigimod PH20 SC in Adult Participants With Bullous Pemphigoid
The main goal of this study is to see if the investigational drug is safe and effective in treating people with bullous pemphigoid (BP). The ... -
Comparison of Anti-coagulation and anti-Platelet Therapies for Intracranial Vascular Atherostenosis
The purpose of this research study is to see whether ticagrelor and aspirin or rivaroxaban and aspirin compared to clopidogrel and aspirin will have the ... -
Impact Of Inclisiran on Major Adverse Cardiovascular Events in Participants with Established Cardiovascular Disease (VICTORION-2 PREVENT)
The purpose of this research study is to determine if the study treatment, an FDA approved drug known to be safe and effective in lowering ... -
A Phase 1b/2 Open-Label Study of Amivantamab Monotherapy and in Addition to Standard-of-Care Chemotherapy in Participants with Advanced or Metastatic Colorectal Cancer.
You can participate in this study if you are diagnosed with histologically or cytologically confirmed unresectable or metastatic adenocarcinoma of the colon or rectum. The ... -
Mitral Valve Screening Survey (MVSS)
Numerous transcatheter mitral valve interventions have emerged as a treatment option for patients with mitral valve disease. Development of transcatheter mitral valve repair (TMVr) and ... -
A Phase 1/1b Open-label Multicenter Study to Investigate the Safety Tolerability Pharmacokinetics and Antitumor Activity of KIN-2787 in Participants with BRAF and/or NRAS Mutation-positive Solid Tumors.
You can participate in this study if you are diagnosed with stage 3 or stage 4 skin melanoma. The purpose of this study is to ... -
An Observational Longitudinal Prospective Long-Term Registry of Patients With Hypophosphatasia
This multinational, multicenter, observational, prospective, long-term registry is designed to collect data on epidemiology, hypophosphatasia (HPP) history, clinical course, symptoms (including systemic aspects of disease ... -
A Prospective Single Arm Open Label Study of the FARAPULSE Pulsed Field Ablation System in Subjects with Persistent Atrial Fibrillation
Prospective, single arm, open label, multi-center IDE pivotal study utilizing the FARAPULSE PFA System in the treatment of patients with Persistent Atrial Fibrillation (AF).
Patients ... -
INHALE-1: A 26-week Primary Treatment Phase with 26-week Extension Open-label Randomized Clinical Trial Evaluating the Efficacy and Safety of Afrezza Versus Rapid-acting Insulin Analog Injections Both in Combination with a Basal Insulin in Pediatric
The purpose of this study is to find out whether an inhaled, ultra-rapid-acting insulin (Afrezza) works as well as rapid-acting injections. The possible benefits of ...