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A Phase 1b/2 Open-Label Study of Amivantamab Monotherapy and in Addition to Standard-of-Care Chemotherapy in Participants with Advanced or Metastatic Colorectal Cancer.
You can participate in this study if you are diagnosed with histologically or cytologically confirmed unresectable or metastatic adenocarcinoma of the colon or rectum. The ...Phase
Interventional
Accepts Healthy Volunteer
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A Phase 2 Open-Label Study to Evaluate Etavopivat for the Treatment of Anemia in Patients with Myelodysplastic Syndromes (MDS).
You can participate in this study if you are diagnosed with Myelodysplastic Syndromes (MDS). In this study we will evaluate the study drug (Etavopivat) for ...Phase
Interventional
Accepts Healthy Volunteer
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A Randomized Open-Label Multicenter Phase 3 Trial of Domvanalimab Zimberelimab and Chemotherapy Versus Nivolumab and Chemotherapy in Participants with Previously-Untreated Locally Advanced Unresectable or Metastatic Gastric Gastroesophageal Junction and Esophageal Adenocarcinoma
This study is designed for patients who have Untreated Locally Advanced Unresectable or Metastatic Gastric, Gastroesophageal Junction, and Esophageal Adenocarcinoma
This is a phase 3 ...
Phase
Interventional
Accepts Healthy Volunteer
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Randomized Double-blind Placebo-Controlled Multicenter Phase 3 Study to Evaluate the Safety Tolerability and Efficacy of XEN1101 as Adjunctive Therapy in Focal-Onset Seizures
In this research a study drug named XEN1101 is being tested for the treatment of seizures. XEN1101 is a study drug because its safety, effectiveness ...Phase
Interventional
Accepts Healthy Volunteer
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A Phase 1/1b Open-label Multicenter Study to Investigate the Safety Tolerability Pharmacokinetics and Antitumor Activity of KIN-2787 in Participants with BRAF and/or NRAS Mutation-positive Solid Tumors.
You can participate in this study if you are diagnosed with stage 3 or stage 4 skin melanoma. The purpose of this study is to ...Phase
Interventional
Accepts Healthy Volunteer
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Comparison of Anti-coagulation and anti-Platelet Therapies for Intracranial Vascular Atherostenosis
The purpose of this research study is to see whether ticagrelor and aspirin or rivaroxaban and aspirin compared to clopidogrel and aspirin will have the ...Phase
Interventional
Accepts Healthy Volunteer
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Impact Of Inclisiran on Major Adverse Cardiovascular Events in Participants with Established Cardiovascular Disease (VICTORION-2 PREVENT)
The purpose of this research study is to determine if the study treatment, an FDA approved drug known to be safe and effective in lowering ...Phase
Interventional
Accepts Healthy Volunteer
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Mitral Valve Screening Survey (MVSS)
Numerous transcatheter mitral valve interventions have emerged as a treatment option for patients with mitral valve disease. Development of transcatheter mitral valve repair (TMVr) and ...Phase N/A Interventional
Accepts Healthy Volunteer
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A Phase 3 Randomized Double-Blind Placebo-Controlled Study to Evaluate the Efficacy and Safety of Deucravacitinib in Participants with Active Systemic Lupus Erythematosus (POETYK-SLE-2)
This study is a double-blinded 52-week clinical trial to evaluate the efficacy and safety of deucravacitinib in adult participants with active Systemic Lupus Erythematosus (SLE ...Phase
Interventional
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A Phase 2 Double-blind Randomized Placebo-controlled Multicenter Study to Evaluate Efficacy Safety and Tolerability of JBT-101 in Systemic Lupus Erythematosus
This research study is being done to test the effect, safety, and tolerability of the experimental drug JBT-101 in subjects with Systemic Lupus Erythematosus (SLE ...Phase
Accepts Healthy Volunteer
